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Opioid exercise is because of both of those small affinity binding in the parent compound and better affinity binding with the O-demethylated metabolite M1 to µ-opioid receptors. In animal products, M1 is around 6 times far more potent than tramadol in generating analgesia and 200 times much more strong in https://jonahh642qzh1.wikicommunication.com/user

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