At an oral dose of 2000 mg/kg/day in rats, maternal toxicity and deaths had been seen with an elevated incidence of early fetal resorption; spontaneous abortions happened in cynomolgus monkeys with the maternally toxic oral dose of 2000 mg/kg/working day; there are no adequate and perfectly-controlled trials in Expecting women; https://vitamink43199.blogvivi.com/35065547/the-best-side-of-km04416