The adaptive immune system of jawed vertebrates generates a highly diverse repertoire of antibodies to meet the antigenic challenges of a constantly evolving biological ecosystem. Most of the diversity is generated by two mechanisms: V(D)J gene recombination and somatic hypermutation (SHM). SHM introduces changes in the variable domain of antibodies. mostly in the regions that form th... https://www.nacrack.com/flash-find-Orthofeet-Edgewater-Men-s-Athletic-Shoe-hot-choice/